Oxyfedrine L-form HCl

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Oxyfedrine hydrochloride，一种血管扩张剂，是一种具有口服活性的 β-肾上腺素受体 (β-adrenoreceptor) 激动剂。Oxyfedrine hydrochloride 可降低冠状血管的张力。Oxyfedrine 可用于心血管疾病的研究。

Oxyfedrine hydrochloride, a vasodilator, is an orally active β-adrenoreceptor agonist. Oxyfedrine decreases the tonicity of coronary vessels. Oxyfedrine hydrochloride can be used in the research of cardiovascular disease.

Oxyfedrine (50 μM, 48 h) suppresses aldehyde dehydrogenase (ALDH) activity in HCT116 and HSC-4 cells.Oxyfedrine (50 μM, 48 h) acts as a sensitizer for GSH-depleting agents, and induces cell death in HCT116 and HSC-4 cells when with the drug combinations.Oxyfedrine (0-1 μg/mL) inhibits spontaneous myogenic activity in rat isolated portal vein.

Oxyfedrine (14 mg/kg, p.o., for 3-4 weeks) shows anti-anginal action in cats. Oxyfedrine (10 mg/kg, i.p., HCT116 cell xenograft mice) suppresses tumor growth when combined with sulfasalazine (SSZ, 350 mg/kg, i.p.).Oxyfedrine (1 mg/kg, i.v.) decreases the arterial and venous blood high blood viscosity (HBV) in ice water stress rats.

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GPCR/G Protein

Adrenergic Receptor

Adrenergic Receptor

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16777-42-7

349.85

C19H24ClNO3

>98% (HPLC)

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C(CCN[C@H]([C@H](O)C1=CC=CC=C1)C)(=O)C2=CC(OC)=CC=C2.Cl

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(-20℃)

With Ice Pack

≥ 2 years