Diloxanide

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Diloxanide 是一种内阿米巴杀虫剂。它被认为是轻度肠阿米巴病或无症状囊肿患者的首选管腔化合物。

Diloxanide is an endomoeba insecticide. It is considered to be the luminal agent of choice for patients with mild enteroamoebiasis or asymptomatic cysts.

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Diloxanide is hydrolyzed in the gastrointestinal tract from its prodrug Diloxanide furoate.Diloxanide furoate (oral administraion; 75-200 mg/kg; 3 days; once daily) is effective at different dose of dayin weanling rats. At 200 mg/kg, 100% of the treated rats are cured and no amoebic lesions are observed in the caecum. Besides, 85%,77%, and 44.4% of the treated rats are cured at the dose 150 mg/kg, 100 mg/kg, and 75 mg/kg, respectively. The ED50 value is 77.9 mg/kg for this agent in rats.

RD 3803 | RD-3803 | RD3803 | Diloxanide | Diloxanid | Diloxanida

Microbiology/Virology

Parasite

TNNI3 Interacting Kinase (TNNI3K)

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579-38-4

234.08

C9H9Cl2NO2

>98% (HPLC)

In Vitro:?DMSO : 33.33 mg/mL (142.39 mM)

CN(C(=O)C(Cl)Cl)c1ccc(O)cc1

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(-20℃)

With Ice Pack

≥ 2 years