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BMS986187
CAS No. 684238-37-7
BMS986187 ( —— )
产品货号. M24699 CAS No. 684238-37-7
BMS986187 是一种新型强效选择性 δ-阿片受体正变构调节剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥454 | 有现货 |
|
| 5MG | ￥738 | 有现货 |
|
| 10MG | ￥1169 | 有现货 |
|
| 25MG | ￥2223 | 有现货 |
|
| 50MG | ￥3246 | 有现货 |
|
| 100MG | ￥4617 | 有现货 |
|
| 500MG | ￥9720 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称BMS986187
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述BMS986187 是一种新型强效选择性 δ-阿片受体正变构调节剂。
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产品描述BMS986187 is a novel Potent and Selective Positive Allosteric Modulators of the delta-Opioid Receptor.
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体外实验BMS-986187?(1 nM-100 uM) produces little or no activity in agonist mode, but in PAM mode (in the presence of an EC20?of leu-enkephalin (in CHO-OPRD1 cells) or endomorphin 1 (in CHO-OPRM1 cells)) produces a response with an EC50?of 48 nM in CHO-OPRD1 cells and 2?μM in CHO-OPRM1 cells.
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体内实验——
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同义词——
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通路Endocrinology/Hormones
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靶点Opioid Receptor
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受体δ-opioid receptor
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研究领域——
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适应症——
化学信息
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CAS Number684238-37-7
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分子量470.6
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分子式C31H34O4
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纯度>98% (HPLC)
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溶解度DMSO:10 mM
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SMILESCC1=CC=CC=C1COC2=CC=C(C=C2)C3C4=C(CC(CC4=O)(C)C)OC5=C3C(=O)CC(C5)(C)C
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Livingston K E , Stanczyk M A , Burford N , et al. Pharmacological Evidence for a Putative Conserved Allosteric Site on Opioid Receptors[J]. Molecular Pharmacology, 2017:mol.117.109561.
产品手册
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