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DAMGO (TFA)
CAS No. 950492-85-0
DAMGO (TFA) ( —— )
产品货号. M30306 CAS No. 950492-85-0
DAMGO is a selective peptide agonist of the μ-opioid receptor .
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥778 | 有现货 |
|
| 10MG | ￥1340 | 有现货 |
|
| 25MG | ￥2781 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称DAMGO (TFA)
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述DAMGO is a selective peptide agonist of the μ-opioid receptor .
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产品描述DAMGO is a selective peptide agonist of the μ-opioid receptor .
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体外实验DAMGO (1-10 μM) TFA significantly reduces the activation of neuronal Akt and ERK1/2 by CXCL12 and inhibits CXCL12-promoted neuronal survival, but does not down-regulate CXCR4 protein expression.DAMGO (1 μM) TFA effectively inhibits the prostaglandin E 2 (PGE 2) induced increase in a tetrodotoxin-resistant voltage-gated Na+ current (TTX-R I Na), i.e. PGE 2 (1 μM) can increase the TTX-R I Na peak by 103 % compared to 24.9 % with the addition of DAMGO.
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体内实验DAMGO (i.v., 0.5-2 mg/kg) TFA can produce significant anti-injury effects on injured paws of male Sprague-Dawley rats weighing 200-225 g in a dose-dependent manner, producing an effective and long-lasting analgesic effect.
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同义词——
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通路Endocrinology/Hormones
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靶点Opioid Receptor
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number950492-85-0
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分子量627.61
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分子式C28H36F3N5O8
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纯度>98% (HPLC)
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溶解度H2O : 125 mg/mL (199.17 mM; Need ultrasonic)
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SMILES——
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化学全称Sequence:Tyr-{d-Ala}-Gly-{Me-Phe}-Gly-ol
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
FEBS Lett. 1995 Jan 2;357(1):93-7. Onogi T, et al. DAMGO, a mu-opioid receptor selective agonist, distinguishes between mu- and delta-opioid receptors around their first extracellular loops.
产品手册
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