2,3-Dihydrobenzofuran ( 2,3-Dihydrobenzofuran )

产品货号. M22654 CAS No. 496-16-2

2,3-二氢苯并呋喃是一种从 L. camara 叶子中分离出来的乙酰胆碱酯酶 (AChE) 抑制剂。香豆素可用作生物农药。 2,3-二氢苯并呋喃是1-苯并呋喃类的一员，是苯并呋喃的2,3-二氢衍生物。它具有代谢物的作用。乙酰胆碱酯酶的体外抑制随着家蝇（头部和胸部）匀浆中香豆素浓度的增加而增加。

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
500MG	获取报价	有现货
1G	获取报价	有现货
1 mL x 10 mM in DMSO	￥94	有现货

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生物学信息

产品名称

2,3-Dihydrobenzofuran
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

2,3-二氢苯并呋喃是一种从 L. camara 叶子中分离出来的乙酰胆碱酯酶 (AChE) 抑制剂。香豆素可用作生物农药。 2,3-二氢苯并呋喃是1-苯并呋喃类的一员，是苯并呋喃的2,3-二氢衍生物。它具有代谢物的作用。乙酰胆碱酯酶的体外抑制随着家蝇（头部和胸部）匀浆中香豆素浓度的增加而增加。
产品描述

2,3-Dihydrobenzofuran is an acetylcholinesterase (AChE) inhibitor isolated from leaves of L. camara.?Coumaran can be used as a biopesticide.?2,3-dihydrobenzofuran is a member of the class of 1-benzofurans that is the 2,3-dihydroderivative of benzofuran.?It has a role as a metabolite.The in vitro inhibition of acetylcholinesterase was increased with the concentration of Coumaran in the housefly (head and thorax) homogenate. Activity of acetylcholinesterase in insects exposed to LC25, LC50, and LC90 doses of Coumaran was markedly inhibited in dose-dependent studies in the head and thorax of housefly and homogenate of stored grain insect pests. The in vivo enzyme inhibition was dose dependent and correlated with the knockdown effect measured at 45 min of exposure in the fumigation bioassay.
体外实验

Cell Viability Assay Cell Line:Promastigotes Concentration:0.4, 0.8 and 1.6 μM Incubation Time:48 h Result: Demonstrated a concentration-dependent reduction in infection of macrophages by 7.0, 22.0 and 33.34% for 0.4, 0.8 and 1.6 μM, respectively.
体内实验

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同义词

2,3-Dihydrobenzofuran
通路

Endocrinology/Hormones
靶点

AChR
受体

AChE|Human Endogenous Metabolite
研究领域

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适应症

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化学信息

CAS Number

496-16-2
分子量

120.15
分子式

C8H8O
纯度

>98% (HPLC)
溶解度

In Vitro:?H2O : 150 mg/mL (1248.44 mM)
SMILES

C1Cc2ccccc2O1
化学全称

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运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1. Rajashekar Y , Raghavendra A , Bakthavatsalam N . Acetylcholinesterase Inhibition by Biofumigant (Coumaran) from Leaves of Lantana camara in Stored Grain and Household Insect Pests[J]. Biomed Research International, 2014, 2014(187019):187019.

计算器

浓度计算器

摩尔计算器

分子量计算器

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