Moxalactam Disodium

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

莫沙内酰胺钠盐是一种抗生素化合物，对大肠杆菌和铜绿假单胞菌比头孢菌素更有效。

Moxalactam sodium salt is an antibiotic compound more effective against Escherichia coli and Pseudomonas aeruginosathan cephalosporins.(In Vitro):Moxalactam (Latamoxef) inhibits 90% of strains of Escherichia coli, Klebsiella species, Proteus species, Morganella morganii, Neisseria gonorrhoeae, Neisseria meningitidis, Haemophilus influenzae and Salmonella species, including strains which are resistant to Cephalothin (HY-B1275A) and Gentamicin (HY-A0276A) at concentrations of less than 1 μg/mL.Moxalactam exhibits moderate activity against P. aeruginosa and is usually active against other species of Pseudomonas, Acinetobacter species are usually resistant to Moxalactam.Moxalactam has marked stability in vitro against a variety of β-lactamases, including that produced by B. fragilis, inhibits production of β-lactamases and does not induce class I β-lactamase.(In Vivo):Moxalactam (Latamoxef) (0-7.4 mg/mouse; s.c.; once) is effective against bacterial infections in mice.

Moxalactam (Latamoxef) inhibits 90% of strains of Escherichia coli, Klebsiella species, Proteus species, Morganella morganii, Neisseria gonorrhoeae, Neisseria meningitidis, Haemophilus influenzae and Salmonella species, including strains which are resistant to Cephalothin (HY-B1275A) and Gentamicin (HY-A0276A) at concentrations of less than 1 μg/mL.Moxalactam exhibits moderate activity against P. aeruginosa and is usually active against other species of Pseudomonas, Acinetobacter species are usually resistant to Moxalactam.Moxalactam has marked stability in vitro against a variety of β-lactamases, including that produced by B. fragilis, inhibits production of β-lactamases and does not induce class I β-lactamase.

Moxalactam (Latamoxef) (0-7.4 mg/mouse; s.c.; once) is effective against bacterial infections in mice. Animal Model:Four-week-old male strain ICR mice, weighing 18-20 g, bacterial infection model Dosage:0-7.4 mg/mouse Administration:Subcutaneous injection, once Result:Showed protective activity with ED50s less than 7.4 mg/mouse against gram-positive and gram-negative bacteria infected mice.

Moxalactam Disodium | Latamoxef, Sodium Salt

Endocrinology/Hormones

AChR

Antibacterial

Infection

——

64953-12-4

564.44

C20H18N6Na2O9S

>98% (HPLC)

DMSO : ≥ 38 mg/mL; 67.32 mM

[H][C@]12OCC(CSC3=NN=NN3C)=C(N1C(=O)[C@]2(NC(=O)[C@H](C(=O)O[Na])C1=CC=C(O)C=C1)OC)C(=O)O[Na]

sodium (6R,7R)-7-(2-carboxylato-2-(4-hydroxyphenyl)acetamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

(-20℃)

With Ice Pack

≥ 2 years