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Loratadine
CAS No. 79794-75-5
Loratadine ( Loratidine | SCH-29851 )
产品货号. M15987 CAS No. 79794-75-5
一种三环抗组胺药，作为外周组胺 H1 受体的选择性反向激动剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 50MG | ￥100 | 有现货 |
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| 100MG | ￥147 | 有现货 |
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| 500MG | ￥348 | 有现货 |
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| 1G | ￥500 | 有现货 |
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| 1 mL x 10 mM in DMSO | ￥136 | 有现货 |
|
生物学信息
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产品名称Loratadine
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述一种三环抗组胺药，作为外周组胺 H1 受体的选择性反向激动剂。
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产品描述A tricyclic antihistamine that acts as a selective inverse agonist of peripheral histamine H1-receptors.Allergy Approved(In Vitro):Loratadine is an antihistamine that inhibits histamine-induced activities of IL-6 and IL-8 secretion in endothelial cells.
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体外实验Loratadine is an antihistamine that inhibits histamine-induced activities of IL-6 and IL-8 secretion in endothelial cells.
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体内实验——
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同义词Loratidine | SCH-29851
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通路GPCR/G Protein
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靶点Histamine Receptor
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受体B(0)AT2
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研究领域Inflammation/Immunology
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适应症Allergy
化学信息
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CAS Number79794-75-5
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分子量382.8832
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分子式C22H23ClN2O2
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纯度>98% (HPLC)
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溶解度10 mM in DMSO
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SMILESCCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1
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化学全称1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Devillier P, et al. Clin Pharmacokinet. 2008;47(4):217-30.
2. Barnett A, et al. Agents Actions. 1984 Jun;14(5-6):590-7.
3. Roman IJ, et al. Clin Rev Allergy. 1993 Spring;11(1):89-110.
