
Arbidol
CAS No. 131707-25-0
Arbidol ( —— )
产品货号. M37226 CAS No. 131707-25-0
Umifenovir 是一种有效的口服活性广谱抗病毒活性分子,对许多包膜病毒和非包膜病毒具有活性。Umifenovir 被用作抗流感病毒剂 (anti-influenza virus)。Umifenovir 能有效抑制病毒与宿主细胞的融合。 Umifenovir 是体外有效的 SARS-CoV-2 的抑制剂。Umifenovir 具有抗炎活性。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥266 | 有现货 |
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10MG | ¥428 | 有现货 |
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25MG | ¥845 | 有现货 |
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50MG | ¥1392 | 有现货 |
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100MG | ¥2043 | 有现货 |
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500MG | ¥5041 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Arbidol
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Umifenovir 是一种有效的口服活性广谱抗病毒活性分子,对许多包膜病毒和非包膜病毒具有活性。Umifenovir 被用作抗流感病毒剂 (anti-influenza virus)。Umifenovir 能有效抑制病毒与宿主细胞的融合。 Umifenovir 是体外有效的 SARS-CoV-2 的抑制剂。Umifenovir 具有抗炎活性。
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产品描述Umifenovir is a potent, orally active broad-spectrum antiviral agent with activity against a number of enveloped and non-enveloped viruses. Umifenovir is used as an anti-influenza virus agent. Umifenovir could effectively inhibit the fusion of virus with host cells. Umifenovir is an efficient inhibitor of SARS-CoV-2 in vitro. Umifenovir shows anti-inflammatory activity.
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体外实验Umifenovir exhibits a wide range and potent antiviral activity against a number of viruses including influenza viruses A, B and C, respiratory syncytial virus, SARS-CoV, adenovirus, parainfluenza type 5, poliovirus 1, rhinovirus 14, coxsackievirus B5, hantaan virus, Chikungunya virus, HBV and HCV.
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体内实验Umifenovir (25 and 45 mg/ml; p.o.) shows a survival benefit to mice suffering from influenza infection.Animal Model:BALB/c mice (6–8 weeks old), mice were intranasally (i.n.) inoculated with 2 times the 50% mouse lethal dose (MLD50) of A/ Guangdong/GIRD07/09 (H1N1) (104.5TCID50/mL) in a volume of 20mL.Dosage:1.25 mg/mL (25 mg/kg/day) and 2.25 mg/mL (45 mg/kg/day) in a total volume of 500mL at one day pre-infection and 3 days post-infection (dpi)Administration:Oral administration Result:Increased the survival rate, inhibited the decrease of body weight at 45 mg/mL and inhibited the increase of mice lung index at 25 mg/mL and 45 mg/mL comparing to virus group.
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同义词——
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通路Immunology/Inflammation
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靶点Antiviral
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受体Antiviral | SARS-CoV
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研究领域——
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适应症——
化学信息
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CAS Number131707-25-0
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分子量477.42
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分子式C22H25BrN2O3S
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO 中的溶解度 : 50 mg/mL (104.73 mM; 超声助溶 )
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SMILESO=C(OCC)C=1C=2C(=CC(Br)=C(O)C2CN(C)C)N(C1CSC=3C=CC=CC3)C
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Julie Blaising, et al. Arbidol as a broad-spectrum antiviral: an update. Antiviral Res. 2014 Jul;107:84-94. doi: 10.1016/j.antiviral.2014.04.006. Epub 2014 Apr 24.?
产品手册




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Arbidol
Umifenovir 是一种有效的口服活性广谱抗病毒活性分子,对许多包膜病毒和非包膜病毒具有活性。Umifenovir 被用作抗流感病毒剂 (anti-influenza virus)。Umifenovir 能有效抑制病毒与宿主细胞的融合。 Umifenovir 是体外有效的 SARS-CoV-2 的抑制剂。Umifenovir 具有抗炎活性。