Torezolid

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Torezolid（TR-701；tedizolid）是一种新型恶唑烷酮，用于治疗革兰氏阳性菌感染。

Torezolid (TR-701; tedizolid) is a novel oxazolidinone for gram-positive infections.(In Vitro):Tedizolid (0.25 μg/mL) inhibits all 28 clinical isolates of PRSP, and is 4-fold more potent than linezolid against PRSP.(In Vivo):For mice infected with PSSP type III, the 100% survival rate is achieved with tedizolid phosphate at a minimum total daily dose of 10 mg/kg. Lungs of infected mice treated with tedizolid phosphate show less severe inflammation and edema, as indicated by the mean scores for inflammation and edema.

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TR-701 | tedizolid

Metabolic Enzyme/Protease

MAO

MAO-A| MAO-B

Infection

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856866-72-3

370.34

C17H15FN6O3

>98% (HPLC)

DMSO: 10 mM

O=C1O[C@@H](CO)CN1C2=CC=C(C3=CC=C(C4=NN(C)N=N4)N=C3)C(F)=C2

(5R)-3-(3-fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one

(-20℃)

With Ice Pack

≥ 2 years