Quercitrin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

槲皮苷是一种植物来源的黄酮类化合物，具有抗氧化和抗炎活性。

Quercitrin is a plant-derived flavonoid compound, displays antioxidant and anti-inflammatory activities. Quercitrin can be found in a number of food items such as garden tomato (var. ), German camomile, endive, and kiwi, which makes quercitrin a potential biomarker for the consumption of these food products.

Cell Proliferation Assay Cell Line:DLD-1 colon cancer cell lines Concentration:5, 10, 25 and 50 μM Incubation Time:24, 48 and 72 hours Result:Time- and Dose-dependently decreased cell proliferation of colorectal carcinoma cells.Apoptosis Analysis Cell Line:DLD-1 colon cancer cell lines Concentration:50 μM Incubation Time:48 and 72 hours Result:Induced cell apoptosis and time- and dose-dependently increased caspase-3 enzyme activity.

Animal Model:Male ICR mice with carbon tetrachloride (CCl4) induced brain injuryDosage:50 and 100 mg/kg Administration:Oral gavage; 50 and 100 mg/kg, once Result:Dose-dependently decreased the levels of ROS and malondialdehyde (MDA) concentration in the hippocampus homogenates, and also dose-dependently decreased the CYP2E1 level in the brains. Increased the activities of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx). Inhibited the N-methyl-D-aspartate receptor 2B subunit (NR2B) level and the activities of monoamine oxidase (MAO) and acetylcholine esterase (AChE) in mouse brains.

Quercitrin | Thujin

Metabolic Enzyme/Protease

MAO

Others

Inflammation/Immunology

——

522-12-3

448.39

C21H20O11

>98% (HPLC)

DMSO : ≥ 31 mg/mL; 69.14 mM

c1(c(c(=O)c2c(cc(cc2o1)O)O)O[C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O)O)c1cc(c(cc1)O)O

2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one

(-20℃)

With Ice Pack

≥ 2 years