AKT/PKB/Rac - Protein Kinase Substrate ( ——— )

产品货号. M41669 CAS No. 324029-01-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

AKT/PKB/Rac - Protein Kinase Substrate
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

AKTide-2T 是一个优良的体外 AKT 底物，可竞争性抑制组蛋白 H2B 磷酸化，其 Ki 值为 12 nM。AKTide-2T 模拟 Akt 的最佳磷酸化序列，是一种抑制肽，是 S22 位置中缺失了 Thr 的野生型AKTide。
产品描述

AKTide-2T is an excellent in vitro substrate for AKT and shows competitive inhibition of histone H2B phosphorylation with a Ki of 12 nM. AKTide-2T mimics the optimal phosphorylation sequence of Akt and is an inhibitory peptide with the wildtype AKTide lacking Thr in the S22 position.
体外实验

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体内实验

AKTide-2T mimics the optimal phosphorylation sequence of Akt, and inhibits Akt phosphorylated Hsp27 by addition of 20 μM Akt inhibitory peptide.
同义词

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通路

Others
靶点

Other Targets
受体

Others
研究领域

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适应症

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1. T Obata,et al. Peptide and protein library screening defines optimal substrate motifs for AKT/PKB. J Biol Chem. 2000 Nov 17;275(46):36108-15.?

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