LEM-14-1189 B ( —— )

产品货号. M36485 CAS No. 2987501-17-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

产品询价大包装询价加入购物车

产品名称

LEM-14-1189 B
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Lem-14-1189, a LEM-14 derivative, is a potent NSD inhibitor of the nuclear receptor binding SET domain, and has inhibitory effects on NSD1, NSD2, and NSD3, with IC50 of 418 μM, 111 μM, and 60 μM, respectively. LEM-14-1189 has potential anticancer activity and can be used to study multiple myeloma (MM) and diseases of the blood system.
产品描述

Lem-14-1189, a LEM-14 derivative, is a potent NSD inhibitor of the nuclear receptor binding SET domain, and has inhibitory effects on NSD1, NSD2, and NSD3, with IC50 of 418 μM, 111 μM, and 60 μM, respectively. LEM-14-1189 has potential anticancer activity and can be used to study multiple myeloma (MM) and diseases of the blood system.
体外实验

——
体内实验

——
同义词

——
通路

Others
靶点

Other Targets
受体

Histone Methyltransferase
研究领域

——
适应症

——

CAS Number

2987501-17-5
分子量

682.81
分子式

C35H34N6O5S2
纯度

>98% (HPLC)
溶解度

——
SMILES

C1CCC2=C(C1)C3=C(S2)N=C(NC3=O)CN(CCCNC(=O)C4=CC5=CC=CC=C5C(=O)O4)CC6=NC7=C(C8=C(S7)CCCC8)C(=O)N6
化学全称

——

计算器

产品手册

关联产品

AC 45594

AC 45594 是类固醇生成因子 1 (SF-1) 的激动剂 (IC50 : 50-100 nM)。
Parimifasor

Parimifasor（LYC-30937-EC，LYC30937）是一种口服生物可利用的肠溶 ATP 酶调节剂，作为肠道定向疗法用于治疗炎症性肠病 (IBD)。
8-O-Acetylharpagide

8-O-Acetylharpagide 对豚鼠分离的平滑肌制剂具有生物活性。