Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride
CAS No. 2376990-30-4
Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride ( —— )
产品货号. M27021 CAS No. 2376990-30-4
沙利度胺-O-酰胺基-PEG2-C2-NH2 盐酸盐包含 E3 连接酶配体和接头。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ¥235 | 有现货 |
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| 10MG | ¥341 | 有现货 |
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| 25MG | ¥554 | 有现货 |
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| 50MG | ¥854 | 有现货 |
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| 100MG | ¥1287 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述沙利度胺-O-酰胺基-PEG2-C2-NH2 盐酸盐包含 E3 连接酶配体和接头。
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产品描述Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride incorporates an E3 ligase ligand and a linker. Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride can be used as an immunomodulator for the treatment of cancer.(In Vitro):PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
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体外实验PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number2376990-30-4
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分子量498.92
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分子式C21H27ClN4O8
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纯度>98% (HPLC)
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溶解度——
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SMILESCl.NCCOCCOCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Uemura M, et al. An in vivo highly antitumor-active tetrazolato-bridged dinuclear platinum(II) complex largely circumvents in vitro cisplatin resistance: two linkage isomers yield the same product upon reaction with 9-ethylguanine but exhibit different cytotoxic profiles. Metallomics. 2012 Jul;4(7):686-92.
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