Lanepitant
CAS No. 170566-84-4
Lanepitant ( —— )
产品货号. M34088 CAS No. 170566-84-4
Lanepitant (LY303870) is a nonpeptide neurokinin-1 (NK-1) antagonist with analgesic activity that inhibits neurogenic dura mater inflammation and is used for the prevention of migraine.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ¥3088 | 有现货 |
|
| 50MG | ¥9179 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Lanepitant
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Lanepitant (LY303870) is a nonpeptide neurokinin-1 (NK-1) antagonist with analgesic activity that inhibits neurogenic dura mater inflammation and is used for the prevention of migraine.
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产品描述Lanepitant (LY303870) is a nonpeptide neurokinin-1 (NK-1) antagonist with analgesic activity that inhibits neurogenic dura mater inflammation and is used for the prevention of migraine.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number170566-84-4
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分子量559.74
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分子式C33H45N5O3
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纯度>98% (HPLC)
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溶解度——
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SMILESC([C@H](CN(CC1=C(OC)C=CC=C1)C(C)=O)NC(CN2CCC(CC2)N3CCCCC3)=O)C=4C=5C(NC4)=CC=CC5
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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HIF-1 alpha 556-574
HIF-1 alpha (556-574) is a hypoxia-inducible factor-1 19-mer fragment. HIF-1 functions as master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1subunit is stabilized in response to a lack of oxygen. This part of HIF-1 binds to the von Hippel-Lindau factor (VHL) an E3 ubiquitin ligase, and the proline 564 is absolutely vital to the binding process.
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Alagebrium chloride
Alagebrium Chloride 是一种高级糖基化终末产物 (AGE) 抑制剂,已被证明可有效降低收缩压并为舒张压患者提供治疗益处。
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alpha-Chaconine
Alpha-Chaconine has anti-inflammatory effect, associated with the suppression of AP-1, and supports its possible therapeutic role for the treatment of sepsis. Alpha-Chaconine also has cytotoxic effects.
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