Orforglipron ( —— )

产品货号. M32937 CAS No. 2212020-52-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Orforglipron
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Orforglipron (LY3502970) (GLP-1 receptor agonist 1) 是一种胰高血糖素样肽 (GLP-1) 受体激动剂，详细信息请参考专利文献 WO2018056453A1 中的化合物 67。
产品描述

Orforglipron (LY3502970) (GLP-1 receptor agonist 1) is a GLP-1 receptor agonist extracted from patent WO2018056453A1, Compound 67.
体外实验

Orforglipron is an incretin secreted from L cells of the small intestine when nutrients pass through the digestive tract, and glucose is transmitted via the GLP-1 receptor. Orforglipron exhibits various actions such as dependent gastric emptying delay, and feeding suppression.
体内实验

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同义词

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通路

GPCR/G Protein
靶点

Glucagon Receptor
受体

Glucagon Receptor
研究领域

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适应症

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CAS Number

2212020-52-3
分子量

882.96
分子式

C48H48F2N10O5
纯度

>98% (HPLC)
溶解度

In Vitro:?DMSO 中的溶解度 : 100 mg/mL (113.26 mM; 超声助溶 (<60°C)
SMILES

[H][C@@]1(CCOC(C)(C)C1)c1ccc2n(c(cc2c1)C(=O)N1CCc2nn(c(c2[C@@H]1C)-n1ccn(-c2ccc3n(C)ncc3c2F)c1=O)-c1cc(C)c(F)c(C)c1)[C@]1(C[C@@H]1C)c1noc(=O)[nH]1
化学全称

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1. Pyrazolopyridine derivative having glp-1 receptor agonist effect. WO2013046136A1.

计算器

产品手册

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