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Calcium channel-modulator-1
CAS No. 136941-70-3
Calcium channel-modulator-1 ( —— )
产品货号. M32746 CAS No. 136941-70-3
Calcium channel-modulator-1是钙离子通道 (calcium channel) 调节剂，阻塞主动脉收缩的 IC50 值为0.8 μM。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2337 | 有现货 |
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| 10MG | ￥3753 | 有现货 |
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| 25MG | ￥5794 | 有现货 |
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| 50MG | ￥7803 | 有现货 |
|
| 100MG | ￥10170 | 有现货 |
|
| 200MG | ￥13770 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Calcium channel-modulator-1
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Calcium channel-modulator-1是钙离子通道 (calcium channel) 调节剂，阻塞主动脉收缩的 IC50 值为0.8 μM。
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产品描述Calcium channel-modulator-1 is a calcium channel modulator; blocks aortic contraction with an IC50 of 0.8 μM.
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体外实验——
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体内实验Oral administration of Calcium channel-modulator-1 (20 mg/kg) causes a 35-37% decrease in systolic blood pressure in spontaneously hypertensive rats. However, iv administration of Calcium channel-modulator-1 to anesthetized spontaneously hypertensive rats causes a decrease in blood pressure which was more pronounced and long-lasting than that of nifedipine.
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同义词——
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通路GPCR/G Protein
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靶点Calcium Channel
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受体Calcium Channel
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研究领域——
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适应症——
化学信息
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CAS Number136941-70-3
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分子量579.45
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分子式C26H24Cl2N2O7S
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纯度>98% (HPLC)
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溶解度——
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SMILESC(OCCCN1S(=O)(=O)C=2C(C1=O)=CC=CC2)(=O)C=3C(C(C(OC)=O)=C(C)NC3C)C4=C(Cl)C(Cl)=CC=C4
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Sunkel CE, et al. Synthesis of 3-[(2,3-dihydro-1,1,3-trioxo-1,2-benzisothiazol-2-yl)alkyl] 1,4-dihydropyridine-3,5-dicarboxylate derivatives as calcium channel modulators. J Med Chem. 1992 Jun 26;35(13):2407-14.?
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