Obtusin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Obtusin 是来自决明子种子，是一种高度选择性和竞争性的人单胺氧化酶-A (hMAO-A) 抑制剂，IC50 为 11.12 μM，Ki 为 6.15 μM。Obtusin 在神经退行性疾病，尤其是焦虑和抑郁中起预防作用。

Obtusin is a natural product.(In Vitro):Nine anthraquinones, aurantio-Obtusin (1), chryso-Obtusin (2), Obtusin (3), chryso-Obtusin-2-O-beta-D-glucoside (4), physcion (5), emodin (6), chrysophanol (7), obtusifolin (8), and obtusifolin-2-O-beta-D-glucoside (9), isolated from an EtOAc-soluble extract of the seeds of Cassia tora, were subjected to in vitro bioassays to evaluate their inhibitory activity against advanced glycation end products (AGEs) formation and rat lens aldose reductase (RLAR).

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Metabolic Enzyme/Protease

MAO

MAO

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70588-05-5

344.319

C18H16O7

>98% (HPLC)

In Vitro:?DMSO : 5 mg/mL (14.52 mM)

COc1cc2C(=O)c3cc(C)c(O)c(OC)c3C(=O)c2c(O)c1OC

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(-20℃)

With Ice Pack

≥ 2 years