RS 8359

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

RS 8359 是单胺氧化酶 A (MAO-A) 的可逆抑制剂，对 A:B 酶类型的选择性比约为 2200。

RS 8359 is a reversible inhibitor of monoamine oxidase A (MAO-A) with a selectivity ratio of about 2200 for the A:B enzyme types. RS 8359 has antidepressant activity.(In Vivo):RS 8359 shows relatively little effect upon blood pressure when administered together with tyramine, thus effectively eliminating the 'cheese' effect which has contributed to the limited clinical use of the classical monoamine oxidase inhibitors. RS 8359 shows little affinity for the common central nervous system receptors and little anticholinergic effect.

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RS 8359 shows relatively little effect upon blood pressure when administered together with tyramine. RS-8359 shows little affinity for the common central nervous system receptors and little anticholinergic effect.

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Metabolic Enzyme/Protease

MAO

Wnt| β-catenin

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105365-76-2

252.277

C14H12N4O

>98% (HPLC)

In Vitro:?DMSO : 50 mg/mL (198.20 mM)

OC1CCc2c1ncnc2Nc1ccc(cc1)C#N

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(-20℃)

With Ice Pack

≥ 2 years