Anhydrotetracycline hydrochloride

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

脱水四环素（盐酸盐）是广谱四环素破坏酶的有效竞争性抑制剂。

Anhydrotetracycline (hydrochloride) is a potent competitive inhibitor of broad-spectrum tetracycline destructase enzymes.(In Vitro):Anhydrotetracycline (hydrochloride), a tetracycline biosynthetic precursor, inhibited Tet50, TetX, TetX-3 degradations of tetracyclines with the IC50s of 210 μM, 41 μM and 3 μM,respectively. Anhydrotetracycline (hydrochloride) inhibited Tet50, TetX, TetX-3 degradations of demeclocycline with the IC50s of 120 μM, 41 μM, 7 μM,respectively. Anhydrotetracycline (hydrochloride) inhibited Tet50, TetX, TetX-3 degradations of chlortetracycline with the IC50s of 210 μM, 75 μM, 26 μM,respectively.

Anhydrotetracycline hydrochloride inhibits Tet(50) (IC50=210 μM),Tet(X) (IC50=41 μM), Tet(X)_3 (IC50=3 μM) degradations of tetracyclines. Anhydrotetracycline hydrochloride inhibits Tet(50) (IC50=210 μM),Tet(X) (IC50=75 μM), Tet(X)_3 (IC50=26 μM) degradations of chlortetracycline. Anhydrotetracycline hydrochloride inhibits Tet(50) (IC50=120 μM),Tet(X) (IC50=41 μM), Tet(X)_3 (IC50=7 μM) degradations of demeclocycline. Anhydrotetracycline hydrochloride inhibits Tet(50) (IC50=210 μM),Tet(X) (IC50=41 μM), Tet(X)_3 (IC50=3 μM) degradations of tetracyclines. Anhydrotetracycline hydrochloride inhibits Tet(50) (IC50=210 μM),Tet(X) (IC50=75 μM), Tet(X)_3 (IC50=26 μM) degradations of chlortetracycline. Anhydrotetracycline hydrochloride inhibits Tet(50) (IC50=120 μM),Tet(X) (IC50=41 μM), Tet(X)_3 (IC50=7 μM) degradations of demeclocycline.

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GPCR/G Protein

Antibacterial

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13803-65-1

462.88

C22H23ClN2O7

>98% (HPLC)

In Vitro:?H2O : 170 mg/mL (367.27 mM)

O=C(C(C1=O)=C(O)C(N(C)C)C2CC3=C(C(C21O)=O)C(O)=C4C(O)=CC=CC4=C3C)N.[H]Cl

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(-20℃)

With Ice Pack

≥ 2 years