Bifemelane hydrochloride ( —— )

产品货号. M24622 CAS No. 62232-46-6

Bifemelane 盐酸盐是一种 MAO 抑制剂。

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
2MG	￥188	有现货
5MG	￥340	有现货
10MG	￥567	有现货
25MG	￥1097	有现货
50MG	￥1786	有现货
100MG	￥2520	有现货
500MG	￥5301	有现货
1G	获取报价	有现货
1 mL x 10 mM in DMSO	￥377	有现货

产品询价大包装询价加入购物车

生物学信息

产品名称

Bifemelane hydrochloride
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Bifemelane 盐酸盐是一种 MAO 抑制剂。
产品描述

Bifemelane hydrochloride is a MAO inhibitor.
体外实验

Bifemelane inhibits MAO-A in a dose-dependent manner, with Kis of 4.2±0.2 and 14.1±0.7 μM in human brain synaptosomes and human liver mitochondria respectively.Bifemelane inhibits MAO-B activities in a dose-dependent manner, with Kis of 46.0±3.6 and 65.2±7.0 μM in human brain synaptosomes and human liver mitochondria respectively.
体内实验

Bifemelane (20-80 mg/kg; i.p.) dose-dependently decreases exploratory activity in the open field test.Bifemelane (20-80 mg/kg; i.p.) decreases immobility time in the forced swim test, although is not clearly dosedependent and has already reached ceiling at 20 mg/kg. Animal Model:Wistar male rats (230-270 g) are induced hypothermia by ReserpineDosage:20, 40, 80 mg/kg Administration:A single i.p. Result:Attenuated the Reserpine-induced hypothermia by a maximum of 10 ℃.
同义词

——
通路

Metabolic Enzyme/Protease
靶点

MAO
受体

MAO
研究领域

——
适应症

——

化学信息

CAS Number

62232-46-6
分子量

305.84
分子式

C18H23NO·HCl
纯度

>98% (HPLC)
溶解度

H2O:<30.58mg/ml;DMSO:<30.58mg/ml
SMILES

CNCCCCOC1=CC=CC=C1CC2=CC=CC=C2.Cl
化学全称

——

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1.Yoshida Y , Kumagai H , Ohkubo Y , et al. Effects of bifemelane on the calcium level and ATP release of the human origin astrocyte clonal cell.[J]. Journal of Pharmacological Sciences, 2006, 102(1):121-128.

计算器

浓度计算器

摩尔计算器

分子量计算器

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