021-51111890
购物车（）
sales@molnova.cn
SP-8356
CAS No. 1454885-45-0
SP-8356 ( —— )
产品货号. M26459 CAS No. 1454885-45-0
SP-8356 是一种有效的口服活性分化簇 147 (CD147) 抑制剂，具有抗动脉粥样硬化作用。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1036 | 有现货 |
|
| 10MG | ￥1663 | 有现货 |
|
| 25MG | ￥2706 | 有现货 |
|
| 50MG | ￥3860 | 有现货 |
|
| 100MG | ￥5049 | 有现货 |
|
| 200MG | ￥6804 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥1093 | 有现货 |
|
生物学信息
-
产品名称SP-8356
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述SP-8356 是一种有效的口服活性分化簇 147 (CD147) 抑制剂，具有抗动脉粥样硬化作用。
-
产品描述SP-8356 is a potent, orally active inhibitor of cluster of differentiation 147 (CD147) with anti-atherosclerotic effects.(In Vitro):In a time- and dose-dependent manner, SP-8356 (5-10?μM; 48 hours) inhibits the growth of various types of breast cancer cell lines. SP-8356 (10?μM; 48 hours) increases the percentage of MDA-MB231 cells in the S phase and decreases caspase-3 and cleaved PARP .(In Vivo):In a xenograft mouse model, SP-8356 (10?mg/kg; i.p.; every three days until the 42nd day) inhibits tumor growth . SP-8356 (50 mg/kg; p.o.; daily one day after carotid artery ligation for three weeks) prevents the formation of plaque and attenuates its vulnerability.
-
体外实验——
-
体内实验——
-
同义词——
-
通路Autophagy
-
靶点Autophagy
-
受体COX-2| ROS
-
研究领域——
-
适应症——
化学信息
-
CAS Number1454885-45-0
-
分子量300.354
-
分子式C18H20O4
-
纯度>98% (HPLC)
-
溶解度——
-
SMILES[H][C@@]12C[C@@]([H])(C(\C=C\c3cc(O)c(O)c(OC)c3)=CC1=O)C2(C)C
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
-
DCC-3116
DCC-3116 is an orally active, selective and potent ULK1/2 inhibitor with anticancer activity.DCC-3116 inhibits autophagy and can be used in cancer research.
-
2,2-Dihydroxy chalco...
2,2'-Dihydroxy chalcone is a potent inhibitor of β-glucuronidase (IC50=1.6±0.2 μM) and lysozyme (IC50=1.4±0.2 μM) release from rat neutrophils stimulated with fMLP/CB.2,2'-Dihydroxy chalcone has inhibitory activity against Escherichia coli, Shigella fowleri, Staphylococcus albicans and Staphylococcus aureus.
-
Insecticidal agent 3...
Insecticidal agent 364 is a selective small molecule inhibitor of rapamycin kinase target protein. Insecticidal agent 364 has antitumor activity, and by inhibiting mTOR, Insecticidal agent 364 aims to disrupt signaling pathways involved in cancer cell growth and survival, thereby potentially inhibiting tumor growth.
