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Sulfadoxine

CAS No. 2447-57-6

Sulfadoxine ( Ro 4-4393 )

产品货号. M13708 CAS No. 2447-57-6

磺胺多辛(Sulphadoxine)是一种长效磺酰胺,通常与其他化合物联合使用,用于治疗呼吸道、泌尿道和疟疾感染。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
500MG ¥264 有现货
1G 获取报价 有现货
1 mL x 10 mM in DMSO ¥397 有现货

生物学信息

  • 产品名称
    Sulfadoxine
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    磺胺多辛(Sulphadoxine)是一种长效磺酰胺,通常与其他化合物联合使用,用于治疗呼吸道、泌尿道和疟疾感染。
  • 产品描述
    Sulfadoxine(Sulphadoxine) is a long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract and malarial infections.(In Vitro):Sulfadoxine(Sulphadoxine) is an ultra-long-lasting sulfonamide. Sulfadoxine is often used in combination with pyrimethamine to treat or prevent malaria. Both drugs are antifolates; they inhibit the production of enzymes involved in the synthesis of folic acid within the parasites. Either drug by itself is only moderately effective in treating malaria, because the parasite Plasmodium falciparum may be able to use exogenous folic acid, i.e. folic acid which is present in the parasite's environment, while in combination, the two substances have a synergistic effect which outbalances that ability.
  • 体外实验
    Sulfadoxine(Sulphadoxine) is an ultra-long-lasting sulfonamide. Sulfadoxine is often used in combination with pyrimethamine to treat or prevent malaria. Both drugs are antifolates; they inhibit the production of enzymes involved in the synthesis of folic acid within the parasites. Either drug by itself is only moderately effective in treating malaria, because the parasite Plasmodium falciparum may be able to use exogenous folic acid, i.e. folic acid which is present in the parasite's environment, while in combination, the two substances have a synergistic effect which outbalances that ability.
  • 体内实验
    ——
  • 同义词
    Ro 4-4393
  • 通路
    Autophagy
  • 靶点
    Autophagy
  • 受体
    DHPS| DHFR
  • 研究领域
    Infection
  • 适应症
    ——

化学信息

  • CAS Number
    2447-57-6
  • 分子量
    310.33
  • 分子式
    C12H14N4O4S
  • 纯度
    >98% (HPLC)
  • 溶解度
    Water: 62 mg/mL (199.78 mM)
  • SMILES
    O=S(C1=CC=C(N)C=C1)(NC2=NC=NC(OC)=C2OC)=O
  • 化学全称
    4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Raman J, et al. Am J Trop Med Hyg. 2010, 82(5):788-94.
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