Sulfadoxine
CAS No. 2447-57-6
Sulfadoxine ( Ro 4-4393 )
产品货号. M13708 CAS No. 2447-57-6
磺胺多辛(Sulphadoxine)是一种长效磺酰胺,通常与其他化合物联合使用,用于治疗呼吸道、泌尿道和疟疾感染。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 500MG | ¥264 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ¥397 | 有现货 |
|
生物学信息
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产品名称Sulfadoxine
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述磺胺多辛(Sulphadoxine)是一种长效磺酰胺,通常与其他化合物联合使用,用于治疗呼吸道、泌尿道和疟疾感染。
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产品描述Sulfadoxine(Sulphadoxine) is a long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract and malarial infections.(In Vitro):Sulfadoxine(Sulphadoxine) is an ultra-long-lasting sulfonamide. Sulfadoxine is often used in combination with pyrimethamine to treat or prevent malaria. Both drugs are antifolates; they inhibit the production of enzymes involved in the synthesis of folic acid within the parasites. Either drug by itself is only moderately effective in treating malaria, because the parasite Plasmodium falciparum may be able to use exogenous folic acid, i.e. folic acid which is present in the parasite's environment, while in combination, the two substances have a synergistic effect which outbalances that ability.
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体外实验Sulfadoxine(Sulphadoxine) is an ultra-long-lasting sulfonamide. Sulfadoxine is often used in combination with pyrimethamine to treat or prevent malaria. Both drugs are antifolates; they inhibit the production of enzymes involved in the synthesis of folic acid within the parasites. Either drug by itself is only moderately effective in treating malaria, because the parasite Plasmodium falciparum may be able to use exogenous folic acid, i.e. folic acid which is present in the parasite's environment, while in combination, the two substances have a synergistic effect which outbalances that ability.
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体内实验——
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同义词Ro 4-4393
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通路Autophagy
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靶点Autophagy
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受体DHPS| DHFR
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研究领域Infection
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适应症——
化学信息
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CAS Number2447-57-6
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分子量310.33
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分子式C12H14N4O4S
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纯度>98% (HPLC)
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溶解度Water: 62 mg/mL (199.78 mM)
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SMILESO=S(C1=CC=C(N)C=C1)(NC2=NC=NC(OC)=C2OC)=O
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化学全称4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Raman J, et al. Am J Trop Med Hyg. 2010, 82(5):788-94.
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