ROCK2-IN-2

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

ROCK2-IN-2 是 ROCK2 的选择性抑制剂（IC50 <1 μM）。

ROCK2-IN-2 is a selective inhibitor of ROCK2 (IC50 of <1 μM). (In Vitro):Rho-associated protein kinase (ROCK) is a member of the serine-threonine protein kinase family including two isoforms, ROCK1 and ROCK2. ROCK2-IN-2 is involved in a number of cellular functions, which include, for example, actin organization, cell adhesion, cell migration, and cytokinesis. ROCK2-IN-2 can be used for research on the treatment of multiple medical disorders, such as fibrosis, inflammatory disorders, autoimmune disorders, and cardiovascular disorders.

Rho-associated protein kinase (ROCK) is a member of the serine-threonine protein kinase family. ROCK, which exists in two isoforms, ROCK1 and ROCK2, is an effector molecule of RhoA, and the RhoA/ROCK signaling pathway is involved in a number of cellular functions, which include, for example, actin organization, cell adhesion, cell migration, and cytokinesis. In addition, the RhoA/ROCK signaling pathway is involved in regulating smooth muscle contraction. Inhibitors of ROCK have been reported to be useful for treating multiple medical disorders, such as fibrosis, inflammatory disorders, autoimmune disorders, and cardiovascular disorders.

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Cell Cycle/DNA Damage

ROCK

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1995065-79-6

360.4

C18H12N6OS

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (277.48 mM)

N(c1nnc(s1)-c1cccc(c1)-c1ncco1)c1ccc2[nH]ncc2c1

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(-20℃)

With Ice Pack

≥ 2 years