Etimizol

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

依替咪唑被证明可以有效缓解由缺氧成分（低压缺氧、放线菌素 D、脑部机械损伤）引起的遗忘症。

Etimizol?was shown to relieve amnesia effectively in the origin of which there is the hypoxic component (hypobaric hypoxia, actinomycin D, mechanical injury of the brain).?(In Vivo):Extracellular application of 5--10 mM/L Etimizol (Ethymisole) exerted a specific effect on the giant neurons of the Coretus corneus isolated nervous system: action potential duration increased significantly, speed of development of its descending phase decreased, as well as the trace hyperpolarization amplitude .The time interval between administration ofetimizol (3 mg/kg) and the onset of learning varied between 0.5 and 3 h in the several series.?Etimizol (Ethymisole) did not facilitate the learning in rats whatever the time of administration and biological modality of reinforcement .?After administration of Etimizol (Ethymisole) at doses of 10 or 1 mg/loop mean residence time of etimizol in the loop was 20.1 and 7.6 min, respectively, with mean standard deviation being 3.1 and 0.8, respectively .

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The time interval between administration ofetimizol (3 mg/kg) and the onset of learning varied between 0.5 and 3 h in the several series. Etimizol (Ethymisole) did not facilitate the learning in rats whatever the time of administration and biological modality of reinforcement . After administration of Etimizol (Ethymisole) at doses of 10 or 1 mg/loop mean residence time of etimizol in the loop was 20.1 and 7.6 min, respectively, with mean standard deviation being 3.1 and 0.8, respectively . Extracellular application of 5--10 mM/L Etimizol (Ethymisole) exerted a specific effect on the giant neurons of the Coretus corneus isolated nervous system: action potential duration increased significantly, speed of development of its descending phase decreased, as well as the trace hyperpolarization amplitude .

Ethimizole | Ethymisol | Ethymisole

Others

Other Targets

H1 receptor

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64-99-3

210.237

C9H14N4O2

>98% (HPLC)

In Vitro:?Ethanol : ≥ 33.33 mg/mL (158.)

CCn1cnc(C(=O)NC)c1C(=O)NC

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(-20℃)

With Ice Pack

≥ 2 years