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(E)-GABAB receptor antagonist 1
CAS No. 1611483-29-4
(E)-GABAB receptor antagonist 1 ( —— )
产品货号. M26186 CAS No. 1611483-29-4
(E)-GABAB 受体拮抗剂 1 降低 GABA 诱导的 IP3（三磷酸肌醇）产生，IC50 为 37.9 μM。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1017 | 有现货 |
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| 10MG | ￥1492 | 有现货 |
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| 25MG | ￥2297 | 有现货 |
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| 50MG | ￥3171 | 有现货 |
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| 100MG | ￥4140 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥941 | 有现货 |
|
生物学信息
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产品名称(E)-GABAB receptor antagonist 1
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述(E)-GABAB 受体拮抗剂 1 降低 GABA 诱导的 IP3（三磷酸肌醇）产生，IC50 为 37.9 μM。
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产品描述(E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM.(E)-GABAB receptor antagonist 1 is a trans-GABAB receptor antagonist 1. GABAB receptor antagonist 1 (compound 14) is a selective and negative allosteric modulator of GABAB (γ-Aminobutyric acid) receptors.(In Vitro):(E)-GABAB receptor antagonist 1 reduces the maximum effect of IP3 in HEK293 cells overexpressing GABAB receptor and Gqi9 protein induced by agonist GABA, but does not alter EC50.
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体外实验(E)-GABAB receptor antagonist 1 (compound 14) decreases agonist GABA-induced maximal effect of IP3 production in HEK293 cells overexpressing GABAB receptors and Gqi9 proteins without changing the EC50.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Adenine phosphoribosyltransferase
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研究领域——
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适应症——
化学信息
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CAS Number1611483-29-4
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分子量304.38
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分子式C18H24O4
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纯度>98% (HPLC)
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溶解度——
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SMILESO=C(O)C(/C=C/C1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1)=O.[(E)]
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Edamura K, et al. No self-injurious behavior was found in HPRT-deficient mice treated with 9-ethyladenine. Pharmacol Biochem Behav. 1998 Oct;61(2):175-9.
产品手册
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