Dehydronitrosonisoldipine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

DeHydraminosoldipine 是一种无菌 α 和包含 TIR 基序 1 的抑制剂，可用于神经退行性疾病的研究。

Dehydronitrosonisoldipine is an inhibitor of sterile α and TIR motif-containing 1 and can be used in studies about neurodegenerative disorders. Dehydronitrosonisoldipine inhibits axon degenration and the Vincristine-activated cADPR production in neurons.(In Vitro):Dehydronitrosonisoldipine exhibits an IC50 of 4 μM in the sterile α and TIR motif-containing 1-dN-expression cells, and decreases the cellular cADPR.

Dehydronitrosonisoldipine exhibits an IC50 of 4 μM in the SARM1-dN-expression cells, and decreases the cellular cADPR in cells expressing SARM1, but not in expressing SAM-TIR cells.

——

——

GPCR/G Protein

Calcium Channel

——

——

——

87375-91-5

370.4

C20H22N2O5

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (269.98 mM)

COC(=O)c1c(C)nc(C)c(C(=O)OCC(C)C)c1-c1ccccc1N=O

——

(-20℃)

With Ice Pack

≥ 2 years