Desmethylbellidifolin ( —— )

产品货号. M24218 CAS No. 2980-32-7

COA

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HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Desmethylbellidifolin
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Desmethylbellidifolin 是从 Gentianella acuta 中提取的天然呫吨酮。 1,3,5,8-四羟基氧杂蒽酮具有解痉作用和抗炎活性。
产品描述

Desmethylbellidifolin is a natural xanthone extracted from Gentianella acuta.?1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity.?Dimethylbellidifolin shows mutagenicity in Salmonella typhimurium TA100, TA98, TA97, and TA2637 by the preincubation method;?it also exhibits at the dose of 200 ug/disk a significant inhibition of the growth of Staphylococcus aureus.
体外实验

1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) attenuates lipopolysaccharide-induced nitric oxide release and proinflammatory cytokine expression in RAW264.7 cells.
体内实验

1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin; orally; 5, 10, 20 mg/kg; 12 days) can inhibit trinitrobenzenesulfonic acid (TNBS)-induced ulcerative colitis (UC), reducing inflammatory response and alleviate colon muscle spasm.
同义词

——
通路

Microbiology/Virology
靶点

Antifection
受体

Anti-infection
研究领域

——
适应症

——

1.Mutagenicities of xanthone derivatives in Salmonella typhimurium TA100, TA98, TA97, and TA2637.Mutat Res. 1985 Jun-Jul;150(1-2):141-6.

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