Disulfamide，一种具有口服活性的利尿剂，碳酸酐酶 (carbonic anhydrase) 抑制剂，其 IC50 值为 0.07 μM。Disulfamide 可通过抑制碳酸酐酶，阻止钠、碳酸氢盐在近曲小管中的重吸收，从而导致利尿。

Carbonic anhydrase inhibitor 6 (化合物 9b) 是一种有效的人碳酸酐酶 (hCA) 抑制剂，对 hCA IX，hCA II，hCA XII 和 hCA I 的 Ki 值分别为 9.7 nM, 35.2 nM, 88.5 nM, and 91.8 nM。

pNNP (Nitrophenylphosphate) can be used as a substrate for the PP2C assay. pNNP inhibits β-carbonic anhydrase and α-carbonate dehydrogenase, as well as H. pylori Helicobacter pylori. pNNP is a weakly active, tissue-nonspecific alkaline phosphatase modifier. pNNP has been shown to inhibit β-carbonic anhydrase and α-carbonate dehydrogenase.