Pralmorelin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Pralmorelin 是 MEK 的口服活性合成肽类似物。 Pralmorelin 是一种生长素释放肽/生长激素分泌受体激动剂，可以选择性刺激生长素释放肽受体并引起生长激素释放，具有抗炎活性。

Pralmorelin is an oral active synthetic peptide analogue of MEK.?Pralmorelin is an auxin releasing peptide/growth hormone secretory receptor agonist, can selectively stimulate ghrelin receptor and cause growth hormone release,?has shown anti-inflammatory activity.An anti-inflammatory role for ghrelin (GHRP-2) in PKC-mediated inflammation of granulosa cells, at least in part, due to its inhibitory effect on PKC-induced activation of p38, JNK and NF-κB, possibly by targeting to MKP-1 and PP2A.An insulin tolerance test (ITT), CRH stimulation test, and GHRP-2 test on 47 patients suspected of having a hypothalamo-pituitary disorder were preformed. The results indicate that the GHRP-2 test may induce ACTH secretion from the pituitary gland through direct stimulation.

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GPCR/G Protein

GHSR

GHS-R

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158861-67-7

817.99

C45H55N9O6

>98% (HPLC)

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NCCCC[C@@H](C(N)=O)NC([C@@H](CC1=CC=CC=C1)NC([C@H](CC2=CNC3=C2C=CC=C3)NC([C@H](C)NC([C@@H](CC4=CC=C5C=CC=CC5=C4)NC([C@@H](C)N)=O)=O)=O)=O)=O.[H]Cl.[H]Cl

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(-20℃)

With Ice Pack

≥ 2 years