[Met5]-Enkephalin, amide TFA

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

[Met5]-脑啡肽，酰胺 TFA 是 δ 阿片受体激动剂以及推定的 ζ (zeta) 阿片受体。

[Met5]-Enkephalin, amide TFA is a δ opioid receptors agonist as well as putative ζ (zeta) opioid receptors.[Met5]-Enkephalin at 0.1 nM, 10 nM, and 1 μM significantly reduces the total number of glial cells in culture. [Met5]-Enkephalin, amide acts via δ-opioid receptor to inhibit pelvic nerve-evoked contractions of cat distal colon. [Met5]-enkephalin causes concentration-dependent, reversible inhibition of pelvic nerve-evoked contractions, with an IC50 value of 2.2 nM. [Met5]enkephalin at a concentration (3 nM) which produces a large inhibition of neurogenic contractions, has no effect on contractions to exogenous acetylcholine.

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5-Methionine-enkephalin amide (TFA)

Endocrinology/Hormones

Opioid Receptor

δ and ζ opioid receptor

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686.7

C29H37F3N6O8S

>98% (HPLC)

H2O:soluble

Oc2ccc(C[C@H](N)C(=O)NCC(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCSC)C(N)=O)cc2.FC(F)(F)C(=O)O

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(-20℃)

With Ice Pack

≥ 2 years