L-Menthol
CAS No. 2216-51-5
L-Menthol ( Levomenthol | D-(-)-Menthol | l-Menthol | Levomentholum | NSC 62788 | NSC62788 )
产品货号. M13534 CAS No. 2216-51-5
薄荷醇是一种共价有机化合物,由合成或从薄荷或其他薄荷油中获得。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 200MG | ¥136 | 有现货 |
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| 500MG | ¥212 | 有现货 |
|
| 1G | ¥318 | 有现货 |
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| 1 mL x 10 mM in DMSO | ¥245 | 有现货 |
|
生物学信息
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产品名称L-Menthol
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述薄荷醇是一种共价有机化合物,由合成或从薄荷或其他薄荷油中获得。
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产品描述Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. It is a waxy, crystalline substance, clear or white in color, which is solid at room temperature and melts slightly above. The main form of menthol occurring in nature is (-)-menthol, which is assigned the (1R,2S,5R) configuration. Menthol has local anesthetic and counterirritant qualities, and it is widely used to relieve minor throat irritation. .(In Vitro):(-)-Menthol (Menthol ) per se does not exhibit antiproliferative activity, but it is able to enhance 1α,25(OH)2D3-mediated growth inhibition in LNCaP cells. At high (-)-Menthol concentrations above 1.6 mM, the cells begin to detach from the culture dish.(-)-Menthol (0.8 mM) can increase [Ca2+]i via transmembrane influx or store release pathways. Peak increase in [Ca2+]i was 102.3±39 nM (n=3) in (-)-Menthol alone and 124.5±51 nM (n=3) in combination of 1α,25(OH)2D3 with (-)-Menthol, respectively.Combination of 1α,25(OH)2D3 with (-)-Menthol (0.8 mM) cooperatively modulates bcl-2 and p21 expression.
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体外实验——
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体内实验——
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同义词Levomenthol | D-(-)-Menthol | l-Menthol | Levomentholum | NSC 62788 | NSC62788
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通路Endocrinology/Hormones
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靶点Opioid Receptor
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受体Opioid Receptor| κ-opioid receptor
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研究领域Other Indications
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适应症——
化学信息
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CAS Number2216-51-5
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分子量156.27
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分子式C10H20O
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纯度>98% (HPLC)
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溶解度Soluble in Water
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SMILESO[C@H]1C(C(C)C)CCC(C)C1
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化学全称(1R)-2-isopropyl-5-methylcyclohexan-1-ol
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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Orphanin FQ (1-11)
Peptide fragment containing amino acids 1-11 of Nociceptin. Potent agonist of the ORL1/KOR-3 receptor (Ki = 55 nM); displays no affinity for opioid receptors, including μ, δ, κ1 and κ3 receptors (Ki >1000 nM). Displays analgesic properties in CD-1 mice.
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