021-51111890
购物车（）
sales@molnova.cn
Adrenorphin(3TFA)
CAS No. 88377-68-8
Adrenorphin(3TFA) ( Metorphamide )
产品货号. M21026 CAS No. 88377-68-8
Adrenorphin(3TFA) 是 μ-阿片受体 (Ki :12 nM) 的激动剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1843 | 有现货 |
|
| 10MG | ￥2746 | 有现货 |
|
| 25MG | ￥4594 | 有现货 |
|
| 50MG | ￥6910 | 有现货 |
|
| 100MG | ￥10080 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥2964 | 有现货 |
|
生物学信息
-
产品名称Adrenorphin(3TFA)
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述Adrenorphin(3TFA) 是 μ-阿片受体 (Ki :12 nM) 的激动剂。
-
产品描述Adrenorphin(3TFA) is an agonist of μ-opioid receptor(Ki :12 nM).
-
体外实验Adrenorphin (Metorphamide) is a opioid octapeptide from bovine brain, acts as a potent agonist of μ-opioid receptor, with Ki of 12 nM. The binding ratios of Ki for μ-opioid receptor/Ki for δ-opioid receptor of 0.04 and of Ki for μ-opioid receptor/Ki for κ-opioid receptor of 0.46. Adrenorphin potently inhibits catecholamine secretion evoked by 10 μM nicotine in cultured human pheochromocytoma 6 cells, with an IC50 of 1.1 μM.
-
体内实验——
-
同义词Metorphamide
-
通路Endocrinology/Hormones
-
靶点Opioid Receptor
-
受体μ-opioid receptor
-
研究领域——
-
适应症——
化学信息
-
CAS Number88377-68-8
-
分子量984.18
-
分子式C44H69N15O9S
-
纯度>98% (HPLC)
-
溶解度DMSO:50 mg/mL (50.80 mM)
-
SMILESCSCCC(NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)C(N)Cc1ccc(O)cc1)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(N)=O)C(C)C
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Miyata A Mizuno K Minamino N et al. Regional distribution of adrenorphin in rat brain: Comparative study with PH-8P[J]. Biochemical and Biophysical Research Communications 1984 120(3):1030-1036.
产品手册
关联产品
-
[Arg14,Lys15]Nocicep...
Highly potent and selective NOP receptor agonist (EC50 = 1 nM). Displays > 875-fold selectivity over opioid receptors (IC50 values are 0.32, 280, > 10000 and 1500 for NOP, μ, δ and κ receptors respectively). Longer lasting and 30-fold more potent than nociceptin in vivo; pronociceptive and inhibits locomotor activity.
-
BMS986188
BMS986188 是一种新型强效选择性 δ-阿片受体正变构调节剂。
-
Enadoline
Enadoline (CI 977;PD 129290) 是一种有效的选择性 κ-阿片受体 (KOR) 激动剂，Ki 为 0.11 nM。
