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GSK2018682
CAS No. 1034688-30-6
GSK2018682 ( —— )
产品货号. M20904 CAS No. 1034688-30-6
GSK2018682 是 1-磷酸鞘氨醇受体 (s1p1) 和 (s1p5) 激动剂（pEC50 分别为 7.7 和 7.2）。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥280 | 有现货 |
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| 5MG | ￥425 | 有现货 |
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| 10MG | ￥710 | 有现货 |
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| 25MG | ￥1349 | 有现货 |
|
| 50MG | ￥2474 | 有现货 |
|
| 100MG | ￥3501 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥467 | 有现货 |
|
生物学信息
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产品名称GSK2018682
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述GSK2018682 是 1-磷酸鞘氨醇受体 (s1p1) 和 (s1p5) 激动剂（pEC50 分别为 7.7 和 7.2）。
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产品描述GSK2018682 is an agonist of sphingosine-1-phosphate receptor ?(s1p1) and (s1p5) agonist(pEC50s of 7.7 and 7.2respectively).(In Vitro):GSK2018682 is an agonist for S1P1 and S1P5 receptor with pEC50s of 7.7 and 7.2, respectively, and has no agonist activity towards human S1P2, S1P3, or S1P4.
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体外实验GSK2018682 is an agonist for S1P1 and S1P5 receptor with pEC50s of 7.7 and 7.2, respectively, and has no agonist activity towards human S1P2, S1P3, or S1P4.
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体内实验——
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同义词——
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通路GPCR/G Protein
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靶点S1P Receptor
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受体S1P
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研究领域Others
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适应症Multiple sclerosis
化学信息
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CAS Number1034688-30-6
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分子量440.88
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分子式C22H21ClN4O4
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纯度>98% (HPLC)
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溶解度DMSO:125 mg/mL (283.52 mM)
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SMILESCC(C)Oc1ncc(-c2nc(-c3cccc4c3ccn4CCCC(=O)O)no2)cc1Cl
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化学全称4-(4-(5-(5-chloro-6-isopropoxypyridin-3-yl)-124-oxadiazol-3-yl)-1H-indol-1-yl)butanoic acid
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Xu J Gray F Henderson A et al. Safety pharmacokinetics pharmacodynamics and bioavailability of GSK2018682 a sphingosine-1-phosphate receptor modulator in healthy volunteers[J]. Clinical Pharmacology in Drug Development 2014 3(3):170-178.
