3-Chloro-L-alanine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

3-Chloro-L-alanine 是一种抑菌氨基酸类似物，可抑制多种酶，包括苏氨酸脱氨酶和丙氨酸消旋酶。

3-Chloro-L-alanine is a bacteriostatic amino acid analog which inhibits a number of enzymes including threonine deaminase and alanine racemase.

β-Chloro-L-alanine can inhibit threonine deaminase, the branched-chain amino acid transaminase (transaminase B), L-aspartate-pdecarboxylase, alanine racemase and probably O-acetylserine sulfhydrylase. β-Chloro-L-alanine reversibly inhibits the Escherichia coli K-12 alanine-valine transaminase, transaminase C. This inhibition, along with the inhibition of transaminase B, account for the isoleucine-plus-valine requirement of Escherichia coli in the presence of β-Chloro-L-alanine. Salmonella typhimurium LT2 will grow in the presence of BCA if isoleucine and valine are added to the medium and presume that the growth requirement is due to the inhibition of transaminase B.

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β-Chloro-L-alanine | L-β-Chloroalanine

GPCR/G Protein

Antibacterial

Bacterial

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2731-73-9

123.54

C3H6ClNO2

>98% (HPLC)

H2O:30 mg/mL (242.84 mM)

N[C@@H](CCl)C(O)=O

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(-20℃)

With Ice Pack

≥ 2 years