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TLR7/8 agonist 1 dihydrochloride
CAS No. 1620278-72-9
TLR7/8 agonist 1 dihydrochloride ( TLR7/8 agonist-5d )
产品货号. M20254 CAS No. 1620278-72-9
TLR7/8 agonist 1 是一种 TLR7/8 激动剂，具有显着的免疫刺激活性。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1017 | 有现货 |
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| 10MG | ￥1644 | 有现货 |
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| 25MG | ￥3060 | 有现货 |
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| 50MG | ￥4585 | 有现货 |
|
| 100MG | ￥6147 | 有现货 |
|
| 200MG | ￥8325 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥938 | 有现货 |
|
生物学信息
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产品名称TLR7/8 agonist 1 dihydrochloride
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述TLR7/8 agonist 1 是一种 TLR7/8 激动剂，具有显着的免疫刺激活性。
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产品描述TLR7/8 agonist 1 is a TLR7/8 agonist which shows prominent immunostimulatory activities.(In Vitro):TLR7/8 agonist 1 (Compound 5d) shows prominent immunostimulatory activities. TLR7/8 agonist 1 serves as a convenient precursor for the covalent attachment of fluorophores without significant loss of activity. TLR7/8 agonist 1 retains TLR7-agonistic activity with an EC50 of 20 nM. TLR7/8 agonist 1 (Compound 1) shows substantially different agonistic potencies in human TLR7 (50 nM) and TLR8 (55 nM) primary screens.
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体外实验TLR7/8 agonist 1 (Compound 5d) shows prominent immunostimulatory activities. TLR7/8 agonist 1 serves as a convenient precursor for the covalent attachment of fluorophores without significant loss of activity. TLR7/8 agonist 1 retains TLR7-agonistic activity with an EC50 of 20 nM. TLR7/8 agonist 1 (Compound 1) shows substantially different agonistic potencies in human TLR7 (50 nM) and TLR8 (55 nM) primary screens.
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体内实验——
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同义词TLR7/8 agonist-5d
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通路Immunology/Inflammation
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靶点TLR
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受体TLR7| TLR8
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研究领域——
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适应症——
化学信息
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CAS Number1620278-72-9
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分子量432.39
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分子式C22H27Cl2N5
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纯度>98% (HPLC)
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溶解度DMSO: 70 mg/mL (161.89 mM)
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SMILESCl.Cl.CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(CN)cc1
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化学全称2-(4-(Aminomethyl)benzyl)-1-butyl-1H-imidazo[45-c]quinolin-4-amine dihydrochloride
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Shukla NM et al. Syntheses of fluorescent imidazoquinoline conjugates as probes of Toll-like receptor 7. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6384-6.
产品手册
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