BI 01383298 ( —— )

产品货号. M20075 CAS No. 2227549-00-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

产品询价大包装询价加入购物车

产品名称

BI 01383298
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

BI 01383298 是柠檬酸钠协同转运蛋白 (SLC13A5) 的选择性抑制剂。
产品描述

BI 01383298 is a selective inhibitor of the sodium-citrate co-transporter (SLC13A5).
体外实验

——
体内实验

——
同义词

——
通路

Membrane Transporter/Ion Channel
靶点

Sodium Channel
受体

SLC13A5
研究领域

——
适应症

——

CAS Number

2227549-00-8
分子量

445.34
分子式

C19H19Cl2FN2O3S
纯度

>98% (HPLC)
溶解度

DMSO: 22 mg/mL (49.4 mM);Water: Insoluble
SMILES

Fc1ccc(CNC(=O)C2CCN(CC2)S(=O)(=O)c2cc(Cl)cc(Cl)c2)cc1
化学全称

1-((35-Dichlorophenyl)sulfonyl)-N-(4-fluorobenzyl)piperidine-4-carboxamide

1.Peters JM. Flipping a citrate switch on liver cancer cells. J Biol Chem. 2017 Aug 18;292(33):13902-13903.

计算器

产品手册

关联产品

Silperisone HCl

Silperisone HCl (RGH-5002) blocks sodium and calcium channels in cells, decreases excitability and contractility of muscle cells, reduces peripheral tone, and acts as a muscle relaxant and peripheral vasodilator. Silperisone HCl is used to treat recurrent painful myoclonus due to spinal cord injury, abnormal hypertonia due to cerebrovascular disease, dystonia symptoms, cone tension syndrome, multiple sclerosis myospasm and myelitis. silperisone is a sodium channel protein type 2 alpha channel blocker. silperisone is an organosilicon similar to tolperisone, an organosilicon compound with centrally acting muscle relaxant properties.
Vernakalant Hydrochl...

Vernakalant hydrochloride 是一种混合电压和频率依赖性的 Na+ 和 K+ 通道阻断剂。Vernakalant 抑制 Kv1.5 channelwt，Kv1.5 channelI508F，Kv1.5 channelT479A，IC50 分别为 13.35±0.93 μM。
AZD 7009

AZD 7009 是一种新型抗心律失常药，可抑制表达 hNav1.5 的 CHO K1 细胞中的晚期钠电流，IC50 为 11 uM。