Nicotine Ditartrate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

(?)-尼古丁是天然生物碱尼古丁的主要形式。它作为神经元烟碱乙酰胆碱受体 (nAChR) 的激动剂，具有成瘾性和致畸性。与 (+)-(R) 对映体相比，(?)-(S)-尼古丁在结合 nAChR 方面显着更活跃，因此尼古丁通常合成为 (?)-(S)-尼古丁，其含量仅为 0.2-1%存在 (+)-(R) 异构体。

(?)-Nicotine is the dominant form of the natural alkaloid nicotine. It acts as an agonist of neuronal nicotinic acetylcholine receptors (nAChRs) and possesses addictive and teratogenic properties. (?)-(S)-Nicotine is significantly more active at binding nAChRs compared to the (+)-(R) antipode thus nicotine is typically synthesized as (?)-(S)-nicotine with only 0.2-1% of the (+)-(R) isomer present.

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(?)-Nicotine Ditartrate

Endocrinology/Hormones

AChR

nAChR

Others

Ulcerative colitis

65-31-6

462.41

C18H26N2O12

>98% (HPLC)

DMSO:198.9 mM

O[C@H]([C@@H](O)C(O)=O)C(O)=O.O[C@H]([C@@H](O)C(O)=O)C(O)=O.CN1CCC[C@H]1c1cccnc1

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(-20℃)

With Ice Pack

≥ 2 years