Alkannin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

紫草素是一种天然红色萘醌色素，具有抗菌、抗肿瘤、抗炎作用；纯化的紫草素制剂广泛用于药品、化妆品和一些食品的生产；紫草素还进入用于治疗烧伤的抗炎软膏和霜组合物中。

Shikonin is a natural red naphthoquinone pigment has antimicrobial anti-tumor and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals cosmetics and some food products; shikonin also enters into the antiinflammatory ointment and cream compositions used for the treatment of burns. It can suppress the cell viability adhesion invasion and migratory ability of MGC-803 cells through TLR2- or NF-κB-mediated pathway.(In Vitro):(-)-Alkannin inhibits HCT-116 and SW-480 cells growth with IC50s of 2.38 and 4.53 μM, respectively.

——

——

Shikonin

PI3K/Akt/mTOR signaling

PI3K

PI3Kα

——

——

517-88-4

288.3

C16H16O5

>98% (HPLC)

DMSO:10 mM

C\C(C)=C\C[C@H](O)C1=CC(=O)c2c(O)ccc(O)c2C1=O

(S)-58-Dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)-14-naphthoquinone

(-20℃)

With Ice Pack

≥ 2 years