Desmopressin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

去氨加压素 (DDAVP) 是抗利尿激素精氨酸加压素的合成类似物。加压素受体 去氨加压素的抗利尿特性导致其用于治疗多尿性疾病，包括原发性夜间遗尿症、夜尿症和尿崩症。

Desmopressin(DDAVP) is the synthetic analogue of the antidiuretic hormone arginine vasopressin.Vasopressin Receptor The antidiuretic properties of desmopressin have led to its use in polyuric conditions including primary nocturnal enuresis nocturia and diabetes insipidus. Desmopressin works by limiting the amount of water that is eliminated in the urine. Desmopressin binds to V2 receptors in renal collecting ducts increasing water reabsorption. It also stimulates release of von Willebrand factor from endothelial cells by acting on the V2 receptor.

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DDAVP | Desmopressin Acetate

GPCR/G Protein

Vasopressin Receptor

Vasopressin receptor 1|vasopressin receptor 1a|Vasopressin receptor 2

Cancer

Cancer metastases; Haemorrhage

16679-58-6

1069.22

C46H64N14O12S2

>98% (HPLC)

DMSO:10mM

NC(=O)CC[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CCSSC[C@H](NC(=O)[C@H](CC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@H](CCCNC(N)=N)C(=O)NCC(N)=O

(S)-1-((4R7S10S13S16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-69121518-pentaoxo-12-dithia-58111417-pentaazacycloicosane-4-carbonyl)-N-((R)-1-((2-amino-2-oxoethyl)amino)-5-guanidino-1-oxopentan-2-yl)pyrrolidine-2-carboxamide

(-20℃)

With Ice Pack

≥ 2 years