Isocarboxazid

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

异卡波肼具有化学式1-苄基-2-(5-甲基-3-异恶唑基羰基)肼-异卡波肼。它是一种单胺氧化酶抑制剂。

Isocarboxazid has the formula 1-benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine-isocarboxazid. It is a monoamine oxidase inhibitor. It is used in the treatment of major depression, dysthymic disorder, atypical disorder, panic disorder and the phobic disorders.

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Animal Model:Twelve male mice of dd strain (20-25 g)Dosage:0, 0.3,1, 3 mg/kg Administration:Intraperitoneally 60 min before intravenous injection of 5-HTP Result:The number of head twitches at 15 and 30 min after 5-HTP was increased.43% 5-HT concentration increased and 22% of 5-HIAA decreased.

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GPCR/G Protein

Histamine Receptor

Others

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59-63-2

231.25

C12H13N3O2

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (432.43 mM)

Cc1cc(no1)C(=O)NNCc2ccccc2

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(-20℃)

With Ice Pack

≥ 2 years