Multi-kinase inhibitor I ( MDK74978 | MDK 74978. Multi-kinase inhibitor I )

产品货号. M17593 CAS No. 778274-97-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Multi-kinase inhibitor I
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

多激酶抑制剂 I 是一种多激酶抑制剂。
产品描述

MDK74978, also known as Multi-kinase inhibitor I, is a Multi-kinase inhibitor. MDK74978 has CAS#778274-97-8. The last 5 digit was used in its name.
体外实验

Multi-kinase inhibitor 1 (compound 68) is a potent multi-kinase inhibitor. The protein kinases represent a large family of proteins, which play a central role in the regulation of a wide variety of cellular processes and maintaining control over cellular function. These kinases include receptor tyrosine kinases, such as platelet derived growth factor receptor kinase(PDGF-R), the receptor kinase for stem cell factor, c-Kit, and non-receptor tyrosine kinases, such as the fusion kinase Bcr-abl.
体内实验

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同义词

MDK74978 | MDK 74978. Multi-kinase inhibitor I
通路

Angiogenesis
靶点

HIF/HIF Prolyl-hydroxylase
受体

Multi-kinase
研究领域

——
适应症

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CAS Number

778274-97-8
分子量

418.38
分子式

C20H17F3N4O3
纯度

>98% (HPLC)
溶解度

In Vitro:?DMSO : 100 mg/mL (239.02 mM)
SMILES

O=C(NCCO)c1ccc(c2ncnc(Nc3ccc(OC(F)(F)F)cc3)c2)cc1
化学全称

N-(2-Hydroxyethyl)-4-[6-[4-(trifluoromethoxy)anilino]pyrimidin-4-yl]benzamide

1.Chang Hsu Y, et al. Oncotarget. 2016 Nov 15

计算器

产品手册

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