Hederacoside C
CAS No. 14216-03-6
Hederacoside C ( Kalopanaxsaponin B | Hederacoside C | Hederoside H1 )
产品货号. M17289 CAS No. 14216-03-6
常春藤苷 C 具有祛痰作用,可缓解感冒、咳嗽、支气管炎。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ¥208 | 有现货 |
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| 10MG | ¥281 | 有现货 |
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| 25MG | ¥449 | 有现货 |
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| 50MG | ¥649 | 有现货 |
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| 100MG | ¥888 | 有现货 |
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| 500MG | ¥2277 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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| 1 mL x 10 mM in DMSO | ¥504 | 有现货 |
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生物学信息
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产品名称Hederacoside C
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述常春藤苷 C 具有祛痰作用,可缓解感冒、咳嗽、支气管炎。
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产品描述Mutant EGFR inhibitor is a selective and potent Mutated EGFR inhibitor, inhibits L858R activating mutant, the Exonl9 deletion activating mutant and the T790M resistance mutant.
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体外实验Western Blot Analysis Cell Line: Caco-2 Concentration:0.1, 1, 10 μM Incubation Time:1 h Result:Reduced the expression of p-p65/p65, p-JNK, p-ERK, and p-p38.RT-PCR Cell Line:RAW 264.7 Concentration:5, 10, 50 μg/mL Incubation Time:1 h Result:Reduced the expressions of IL-1β, IL-6, TNF-α, and IL-10.
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体内实验Animal Model:TNBS-induced colitis in rat Dosage:0.625, 1.25, 2.5 mg/kg Administration:i.p.Result:Decreased the levels of inflammatory cytokines, including TNF-α, IL-6, IL-1β, CXCL-1, CXCL-2, and CXCL-5.Reduced cell apoptosis in TNBS-induced colitis.Reduced Bax/Bcl-2 ratio, cleaved caspase 3, and p53 protein levels in a dose-dependent manner.
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同义词Kalopanaxsaponin B | Hederacoside C | Hederoside H1
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通路GPCR/G Protein
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靶点Histamine Receptor
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受体Others
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研究领域Infection
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适应症——
化学信息
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CAS Number14216-03-6
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分子量1221.39
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分子式C59H96O26
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (81.87 mM)
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SMILES[C@@H]1([C@@H](OC[C@@H]([C@@H]1O)O)O[C@@H]1[C@]([C@H]2[C@@]([C@@H]3[C@]([C@]4(C(=CC3)[C@H]3[C@@](CC4)(CCC(C3)(C)C)C(=O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO[C@H]3[C@@H]([C@H]([C@H](O[C@H]4[C@@H]([C@@H]([C@H]([C@@H](O4)C)O)O)O)[C@H](O3)CO)O)O)O)O)O)C)(CC2)C)(CC1)C)(CO)C)O[C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O)O
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化学全称Olean-12-en-28-oic acid, 3- ((2-O-(6-deoxy-alpha-L-mannopyranosyl)-alpha-L-arabinopyranosyl)oxy)-23-hydroxy-, O-6-deoxy-alpha-L-mannopyranosyl-(1-4)-O-beta-D-glucopyranosyl-(1-6)-beta-D-glucopyranosyl ester, (3beta,4alpha)-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Kim JM, et al. Xenobiotica. 2013 Nov;43(11):985-92.;
产品手册
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