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Bicyclol
CAS No. 118159-48-1
Bicyclol ( Bicyclol | SY 801 | SY-801 | SY801 )
产品货号. M17171 CAS No. 118159-48-1
Bicyclol(SY 801) 是一种抗肝炎药。口服双环醇可使慢性病毒性乙型和丙型肝炎升高的血清转氨酶（ALT、AST）正常化50%，并且对HBV和HCV复制也有一定程度的抑制作用。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥459 | 有现货 |
|
| 10MG | ￥784 | 有现货 |
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| 25MG | ￥1628 | 有现货 |
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| 50MG | ￥2399 | 有现货 |
|
| 100MG | ￥3294 | 有现货 |
|
| 500MG | ￥7362 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥459 | 有现货 |
|
生物学信息
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产品名称Bicyclol
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Bicyclol(SY 801) 是一种抗肝炎药。口服双环醇可使慢性病毒性乙型和丙型肝炎升高的血清转氨酶（ALT、AST）正常化50%，并且对HBV和HCV复制也有一定程度的抑制作用。
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产品描述Bicyclol, also known as SY 801, is a hepatoprotective agent. Bicyclol upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia. Bicyclol induces cell cycle arrest and autophagy in HepG2 human hepatocellular carcinoma cells through the PI3K/AKT and Ras/Raf/MEK/ERK pathways. Bicyclol attenuates tetracycline-induced fatty liver associated with inhibition of hepatic ER stress and apoptosis in mice. Bicyclol promotes toll-like 2 receptor recruiting inosine 5'-monophosphate dehydrogenase II to exert its anti-inflammatory effect.
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体外实验——
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体内实验——
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同义词Bicyclol | SY 801 | SY-801 | SY801
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通路GPCR/G Protein
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靶点Histamine Receptor
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受体HBV
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研究领域Infection
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适应症——
化学信息
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CAS Number118159-48-1
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分子量390.34
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分子式C19H18O9
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纯度>98% (HPLC)
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溶解度DMSO : ≥ 68 mg/mL. 174.21 mM
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SMILESCOc1c2c(c(c(c1)CO)c1c3c(c(cc1C(=O)OC)OC)OCO3)OCO2
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化学全称5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bi-1,3-benzodioxole]-5-carboxylic acid, methyl ester
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Walsh, S.W., Y. Wang, and A. Killian, AA-2414, J Pharmacol Exp Ther, 1999. 290(1): p. 220-6.
