Bicyclol

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Bicyclol(SY 801) 是一种抗肝炎药。口服双环醇可使慢性病毒性乙型和丙型肝炎升高的血清转氨酶（ALT、AST）正常化50%，并且对HBV和HCV复制也有一定程度的抑制作用。

Bicyclol, also known as SY 801, is a hepatoprotective agent. Bicyclol upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia. Bicyclol induces cell cycle arrest and autophagy in HepG2 human hepatocellular carcinoma cells through the PI3K/AKT and Ras/Raf/MEK/ERK pathways. Bicyclol attenuates tetracycline-induced fatty liver associated with inhibition of hepatic ER stress and apoptosis in mice. Bicyclol promotes toll-like 2 receptor recruiting inosine 5'-monophosphate dehydrogenase II to exert its anti-inflammatory effect.

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Bicyclol | SY 801 | SY-801 | SY801

GPCR/G Protein

Histamine Receptor

HBV

Infection

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118159-48-1

390.34

C19H18O9

>98% (HPLC)

DMSO : ≥ 68 mg/mL. 174.21 mM

COc1c2c(c(c(c1)CO)c1c3c(c(cc1C(=O)OC)OC)OCO3)OCO2

5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bi-1,3-benzodioxole]-5-carboxylic acid, methyl ester

(-20℃)

With Ice Pack

≥ 2 years