Esmolol hydrochloride

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

艾司洛尔盐酸盐是一种 β 肾上腺素能受体阻滞剂。

Esmolol Hydrochloride is a beta adrenergic receptor blocker. (In Vitro):Esmolol hydrochloride is the hydrochloride salt form of Esmolol, a short and rapid-acting beta adrenergic antagonist belonging to the class II anti-arrhythmic drugs and devoid of intrinsic sympathomimetic activity. Esmolol hydrochloride competitively blocks beta-1 adrenergic receptors in cardiac muscle and reduces the contractility and cardiac rate of heart muscle, thereby decreasing cardiac output and myocardial oxygen demands. This agent also decreases sympathetic output centrally and blocks renin secretion. At higher doses, Esmolol hydrochloride also blocks beta-2 receptors located in bronchial and vascular smooth muscle, thereby leading to smooth muscle relaxation.

Esmolol hydrochloride is the hydrochloride salt form of Esmolol, a short and rapid-acting beta adrenergic antagonist belonging to the class II anti-arrhythmic drugs and devoid of intrinsic sympathomimetic activity. Esmolol hydrochloride competitively blocks beta-1 adrenergic receptors in cardiac muscle and reduces the contractility and cardiac rate of heart muscle, thereby decreasing cardiac output and myocardial oxygen demands. This agent also decreases sympathetic output centrally and blocks renin secretion. At higher doses, Esmolol hydrochloride also blocks beta-2 receptors located in bronchial and vascular smooth muscle, thereby leading to smooth muscle relaxation.

——

ASL 8052

Endocrinology/Hormones

Adrenergic Receptor

β-adrenergic receptor

Cardiovascular Disease

——

81161-17-3

331.15

C16H25NO4·HCl

>98% (HPLC)

Ethanol: 66 mg/mL (198.89 mM); Water: 66 mg/mL (198.89 mM); DMSO: 66 mg/mL (198.89 mM)

CC(C)NCC(COC1=CC=C(C=C1)CCC(=O)OC)O.Cl

methyl 3-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]propanoate;hydrochloride

(-20℃)

With Ice Pack

≥ 2 years