Triprolidine hydrochloride

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Triprolidine hydrochloride monohydrate 属于第一代抗组胺试剂，是一种具有口服活性的组胺 H1 (histamine H1) 拮抗剂，可用于过敏性鼻炎的研究。在大鼠中， Triprolidine hydrochloride monohydrate 能阻滞脊髓运动和知觉。

Histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. It is a component of COUGH and COLD medicines. It may cause drowsiness.(In Vivo):Triprolidine hydrochloride monohydrate (292.81-1467.20 μg/kg; intrathecal injection) produces a dose-dependent effect of spinal motor and sensory block in rats.

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Triprolidine hydrochloride monohydrate (292.81-1467.20 μg/kg; intrathecal injection) produces a dose-dependent effect of spinal motor and sensory block in rats. Animal Model:Male Sprague-Dawley rat (300-350 g)Dosage:292.81 μg/kg, 488.02 μg/kg, 733.60μg/kg, 1098.83 μg/kg, 1467.20 μg/kg Administration:Intrathecal injection Result:Elicited a dose-dependent spinal block.

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GPCR/G Protein

Histamine Receptor

H1 receptor

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6138-79-0

314.85

C19H23ClN2

>98% (HPLC)

Soluble in Water

CC1=CC=C(C=C1)/C(=C\CN2CCCC2)/C3=CC=CC=N3.Cl

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(-20℃)

With Ice Pack

≥ 2 years