4-Hydroxy-3-methoxymandelic acid

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

香兰基扁桃酸 (VMA) 是合成人造香草香料的化学中间体，是儿茶酚胺、肾上腺素和去甲肾上腺素的终末代谢产物。

Vanillyl mandelic acid (VMA) is a chemical intermediate in the synthesis of artificial vanilla flavorings and is an end-stage metabolite of the catecholamines, epinephrine, and norepinephrine. It is produced via intermediary metabolites.

Vanillylmandelic acid has antioxidant activity, the IC50 value is determined as the amount of VMA required to reduce 50% of the starting concentration of free radical is 33*10-6 M in the UV-Vis decolourisation DPPH assay.

Vanillylmandelic acid (intra-arterial injection over 1 min; 1, 10 and 100 mg/kg; the 60 min-observation period) produces a significant difference between vanillylmandelic acid groups and controls. Vanillylmandelic acid decreases the heart rate by 17.5%, 17.9% and 18.9% after 1, 10 and 100 mg/kg, respectively. Mean blood pressure is decreased by 13.5% in control animals as compared to 37%, 23% and 26% after 1, 10 and 100 mg/kg, respectively, in wistar rats.

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Others

Other Targets

Others

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55-10-7

198.17

C9H10O5

>98% (HPLC)

Limited solubility

COC1=C(O)C=CC(=C1)C(O)C(O)=O

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(-20℃)

With Ice Pack

≥ 2 years