021-51111890
购物车（）
sales@molnova.cn
Azide-PEG3-Desthiobiotin
CAS No. 1426828-06-9
Azide-PEG3-Desthiobiotin ( —— )
产品货号. M35075 CAS No. 1426828-06-9
Azide-PEG3-Desthiobiotin 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。Azide-PEG3-Desthiobiotin 是一种点击化学试剂。它含有 Azide 基团，可以和含有 Alkyne 基团的分子发生铜催化的叠氮-炔环加成反应（CuAAc)。还可以和含有 DBCO 或 BCN 基团的分子发生菌株促进的炔-叠氮环加成反应 (SPAAC)。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥710 | 有现货 |
|
| 10MG | ￥1169 | 有现货 |
|
| 25MG | ￥2409 | 有现货 |
|
| 50MG | ￥3692 | 有现货 |
|
| 100MG | ￥5274 | 有现货 |
|
| 200MG | ￥7101 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Azide-PEG3-Desthiobiotin
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述Azide-PEG3-Desthiobiotin 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。Azide-PEG3-Desthiobiotin 是一种点击化学试剂。它含有 Azide 基团，可以和含有 Alkyne 基团的分子发生铜催化的叠氮-炔环加成反应（CuAAc)。还可以和含有 DBCO 或 BCN 基团的分子发生菌株促进的炔-叠氮环加成反应 (SPAAC)。
-
产品描述Azide-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azide-PEG3-Desthiobiotin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
-
体外实验PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
-
体内实验——
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体Others
-
研究领域——
-
适应症——
化学信息
-
CAS Number1426828-06-9
-
分子量414.5
-
分子式C18H34N6O5
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESC(CCCCC(NCCOCCOCCOCCN=[N+]=[N-])=O)[C@@H]1[C@H](C)NC(=O)N1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562?
产品手册
关联产品
-
Geranyl linalool
Geranyl linalool is a fragrance ingredient extracted from Brunfelsia uniflora with potential insecticide, antibacterial, antioxidant and anticancer activities.
-
2-chloro-5-(16,18-di...
2-氯-5-(16,18-二氧代-17-氮杂五环[6.6.5.0~2,7~.0~9,14~.0~15,19~]nonadeca-2,4,6,9, 11,13-己烯-17-基)苯甲酸是一种化合物
-
Betulinic acid methy...
Betulinic acid methyl ester showed antiplasmodial activity against chloroquine-resistant Plasmodium falciparum parasites in vitro.It also inhibited B16 2F2 cell proliferation by induction of apoptosis.
