Methocarbamol ( AHR 85 | Guaiacol Glyceryl Ether Carbamate | Guaiphenesin Carbamate | NSC 170960 )

产品货号. M14894 CAS No. 532-03-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Methocarbamol
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

美索巴莫是一种中枢性肌肉松弛剂，用于治疗骨骼肌痉挛。
产品描述

Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms.(In Vitro):Methocarbamol (2?mM; for 20?min) significantly increases the decay times of the EPCs and those of the EPPs induced by the phrenic nerve stimulation.Methocarbamol has no effect on Nav1.7 currents. (In Vivo):Methocarbamol (200?mg/kg; ip) has Muscle relaxant activity of 88.96%.
体外实验

Methocarbamol (2?mM; for 20?min) significantly increases the decay times of the EPCs and those of the EPPs induced by the phrenic nerve stimulation.Methocarbamol has no effect on Nav1.7 currents.
体内实验

Methocarbamol (200?mg/kg; ip) has Muscle relaxant activity of 88.96%. Animal Model:Mice with weight 20-30?g Dosage:200?mg/kg Administration:IP; single dose Result:Had Muscle relaxant activity of 88.96%.
同义词

AHR 85 | Guaiacol Glyceryl Ether Carbamate | Guaiphenesin Carbamate | NSC 170960
通路

Membrane Transporter/Ion Channel
靶点

Carbonic Anhydrase
受体

CA1
研究领域

Metabolic Disease
适应症

——

CAS Number

532-03-6
分子量

241.24
分子式

C11H15NO5
纯度

>98% (HPLC)
溶解度

Ethanol: 48 mg/mL (198.97 mM); Water: 2 mg/mL (8.29 mM); DMSO: 48 mg/mL (198.97 mM)
SMILES

COC1=CC=CC=C1OCC(COC(=O)N)O
化学全称

[2-hydroxy-3-(2-methoxyphenoxy)propyl] carbamate

1.Parr JS, Khalifah RG. J Biol Chem. 1992 Dec 15; 267(35):25044-50.

计算器

产品手册

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