Benfotiamine ( Benzoylthiamine monophosphate )

产品货号. M13604 CAS No. 22457-89-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Benfotiamine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

苯磷硫胺，一种脂溶性硫胺素衍生物，用于治疗糖尿病神经病变。
产品描述

Benfotiamine, the lipid-soluble thiamine derivative used as a treatment for diabetic neuropathy, can inhibit three major pathways(the hexosamine pathway, the advanced glycation end product (AGE) formation pathway and the diacylglycerol (DAG)protein kinase C (PKC) pathway）of hyperglycemic damage and prevent experimental diabetic retinopathy. Benfotiamine is a synthetic S-acyl derivative of thiamine (vitamin B1) for treating sciatica and other painful nerve conditions. More effective at increasing thiamin levels in blood and tissues than water-soluble salts like the previous vitamin B1.
体外实验

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体内实验

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同义词

Benzoylthiamine monophosphate
通路

Others
靶点

Other Targets
受体

Others
研究领域

Neurological Disease
适应症

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CAS Number

22457-89-2
分子量

466.46
分子式

C19H23N4O6PS
纯度

>98% (HPLC)
溶解度

Soluble in DMSO
SMILES

O=C(S/C(CCOP(O)(O)=O)=C(N(CC1=CN=C(C)N=C1N)C=O)/C)C2=CC=CC=C2
化学全称

(Z)-S-(2-(N-((4-amino-2-methylpyrimidin-5-yl)methyl)formamido)-5-(phosphonooxy)pent-2-en-3-yl) benzothioate

1.Bozic I, et al. PLoS One. 2015 Feb 19;10(2):e0118372.

计算器

产品手册

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