CM 346

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

阿福巴唑 (CM346) 是一种抗焦虑药；产生抗焦虑和神经保护作用，但没有任何镇静或肌肉松弛作用。

Afobazole (CM346) is an anxiolytic drug; produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions.(In Vitro):Afobazole's mechanism of action remains poorly defined however, with GABAergic, NGF and BDNF release promoting, MT1 receptor antagonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Afobazole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Afobazole has found little clinical use outside of Russia and has not been evaluated by the FDA.

Afobazole's mechanism of action remains poorly defined however, with GABAergic, NGF and BDNF release promoting, MT1 receptor antagonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Afobazole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Afobazole has found little clinical use outside of Russia and has not been evaluated by the FDA.

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Obenoxazine

Others

Other Targets

Others

Neurological Disease

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173352-21-1

307.41

C15H21N3O2S

>98% (HPLC)

Soluble in DMSO

CCOC1=CC=C2C(N=C(SCCN3CCOCC3)N2)=C1

4-(2-((5-ethoxy-1H-benzo[d]imidazol-2-yl)thio)ethyl)morpholine

(-20℃)

With Ice Pack

≥ 2 years